Tmprss15 | transmembrane protease, serine 15

GeneMGI:1197523Synonyms: enterokinase, A130097D21Rik, +2 more

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Growth/size/body region Hematopoietic system

16 No significant impact

4 Not tested

Gene metrics:7Significant phenotypes
2Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

decreased body weight4 supporting datasetsTmprss15tm1a(KOMP)WtsihomozygoteEarly adult2.57x10-10 
increased circulating sodium level1 supporting datasetTmprss15tm1a(KOMP)WtsihomozygoteEarly adult1.15x10-5 
increased circulating amylase level1 supporting datasetTmprss15tm1a(KOMP)WtsihomozygoteEarly adult4.48x10-10 
increased blood urea nitrogen level1 supporting datasetTmprss15tm1a(KOMP)WtsihomozygoteEarly adult2.61x10-6 
increased leukocyte cell number1 supporting datasetTmprss15tm1a(KOMP)WtsihomozygoteEarly adult9.59x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tmprss15tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Tmprss15tm2a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Tmprss15tm43800(L1L2_st2)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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