Irx3 | Iroquois related homeobox 3

GeneMGI:1197522

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Vision/eye Behavior/neurological Skeleton Craniofacial

13 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



abnormal snout morphology	1 supporting dataset	Irx3^em2(IMPC)H	homozygote	Early adult	2.01x10^-5
increased grip strength	1 supporting dataset	Irx3^em2(IMPC)H	homozygote	Late adult	1.3x10^-6
abnormal cornea morphology	1 supporting dataset	Irx3^em2(IMPC)H	homozygote	Early adult	1.25x10^-5
decreased bone mineral content	1 supporting dataset	Irx3^em2(IMPC)H	homozygote	Early adult	8.9x10^-5
decreased fasting circulating glucose level	1 supporting dataset	Irx3^em2(IMPC)H	homozygote	Early adult	8.86x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Irx3.

Associated images

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Histopathology

There is no histopathology data found for Irx3.

IMPC related publications

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External links

No external links available for Irx3.

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*Irx3^em1(IMPC)H*	Indel	‌	mouse
*Irx3^em2(IMPC)H*	Indel	‌	mouse
*Irx3^tm1(KOMP)Mbp*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector es cell

My Genes