Irx1 | Iroquois homeobox 1
GeneMGI:1197515
Physiological systems
21 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Embryo Growth/size/body region Behavior/neurological Craniofacial Mortality/aging
15 No significant impact
3 Not tested
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues
| preweaning lethality, complete penetrance | 1 supporting dataset | Irx1tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Irx1tm1.1(KOMP)Vlcg | homozygote | E12.5 | N/A * | ||
| embryonic growth retardation | 1 supporting dataset | Irx1tm1.1(KOMP)Vlcg | homozygote | E12.5 | N/A * | ||
| abnormal craniofacial morphology | 1 supporting dataset | Irx1tm1.1(KOMP)Vlcg | homozygote | E12.5 | N/A * | ||
| decreased thigmotaxis | 2 supporting datasets | Irx1tm1.1(KOMP)Vlcg | heterozygote | Early adult | 3.07x10-5 | ||
| abnormal abdominal wall morphology | 1 supporting dataset | Irx1tm1.1(KOMP)Vlcg | homozygote | E12.5 | N/A * | ||
| decreased locomotor activity | 1 supporting dataset | Irx1tm1.1(KOMP)Vlcg | heterozygote | Early adult | 2.37x10-5 | ||
| increased circulating potassium level | 1 supporting dataset | Irx1tm1.1(KOMP)Vlcg | heterozygote | Early adult | 2.92x10-5 |
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External links
No external links available for Irx1.
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