Fzd1 | frizzled class receptor 1

GeneMGI:1196625Synonyms: Fz1, FZ-1

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Immune system Integument Hematopoietic system Behavior/neurological

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased thigmotaxis	4 supporting datasets	Fzd1^em1(IMPC)Mbp	homozygote	Early adult	2.07x10^-8
decreased locomotor activity	9 supporting datasets	Fzd1^em1(IMPC)Mbp	homozygote	Early adult	7.81x10^-59
increased freezing behavior	2 supporting datasets	Fzd1^em1(IMPC)Mbp	homozygote	Early adult	3.69x10^-34
increased lymphocyte cell number	1 supporting dataset	Fzd1^em1(IMPC)Mbp	homozygote	Early adult	1.31x10^-10
decreased exploration in new environment	2 supporting datasets	Fzd1^em1(IMPC)Mbp	homozygote	Early adult	6.74x10^-13
abnormal freezing behavior	1 supporting dataset	Fzd1^em1(IMPC)Mbp	homozygote	Early adult	8.36x10^-6
increased leukocyte cell number	1 supporting dataset	Fzd1^em1(IMPC)Mbp	homozygote	Early adult	1.58x10^-7
abnormal behavior	1 supporting dataset	Fzd1^em1(IMPC)Mbp	homozygote	Early adult	2.43x10^-8
increased monocyte cell number	1 supporting dataset	Fzd1^em1(IMPC)Mbp	homozygote	Early adult	7.93x10^-5
increased eosinophil cell number	1 supporting dataset	Fzd1^em1(IMPC)Mbp	homozygote	Early adult	1.79x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fzd1.

Associated images

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Histopathology

There is no histopathology data found for Fzd1.

IMPC related publications

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External links

No external links available for Fzd1.

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*Fzd1^em1(IMPC)Mbp*	Whole-gene deletion	‌	mouse
*Fzd1^{tm378261(Ifitm2_intron_L1L2_GT0_LF2A_LacZ_BetactP_neo)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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