Mrpl23 | mitochondrial ribosomal protein L23

GeneMGI:1196612Synonyms: Rpl23l, L23mrp

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Behavior/neurological Skeleton Mortality/aging

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Allele:

Phy. System:



preweaning lethality, complete penetrance	1 supporting dataset	Mrpl23^{tm2b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
decreased bone mineral content	2 supporting datasets	Mrpl23^em1(IMPC)H	homozygote	Early adult	1.46x10^-5
increased grip strength	1 supporting dataset	Mrpl23^em1(IMPC)H	homozygote	Early adult	8.19x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mrpl23.

Associated images

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Histopathology

There is no histopathology data found for Mrpl23.

IMPC related publications

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External links

No external links available for Mrpl23.

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*Mrpl23^em1(IMPC)H*	Exon Deletion	‌	mouse
*Mrpl23^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Mrpl23^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Mrpl23^{tm2b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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