Champ1 | chromosome alignment maintaining phosphoprotein 1

GeneMGI:1196398Synonyms: D8Ertd569e, Zfp828, +1 more

Physiological systems

22 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Embryo Growth/size/body region Hematopoietic system Behavior/neurological Cardiovascular system Mortality/aging

14 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal placenta morphology	1 supporting dataset	Champ1^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
abnormal placenta vasculature	1 supporting dataset	Champ1^em1(IMPC)Mbp	heterozygote	E15.5	N/A ^*
edema	1 supporting dataset	Champ1^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
decreased locomotor activity	1 supporting dataset	Champ1^em1(IMPC)Mbp	heterozygote	Early adult	7.96x10^-5
abnormal placenta morphology	1 supporting dataset	Champ1^em1(IMPC)Mbp	heterozygote	E15.5	N/A ^*
abnormal blood vessel morphology	1 supporting dataset	Champ1^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
decreased exploration in new environment	2 supporting datasets	Champ1^em1(IMPC)Mbp	heterozygote	Early adult	7.74x10^-9
abnormal placenta vasculature	1 supporting dataset	Champ1^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
enlarged spleen	1 supporting dataset	Champ1^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Champ1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Champ1.

Associated images

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Histopathology

There is no histopathology data found for Champ1.

IMPC related publications

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External links

No external links available for Champ1.

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*Champ1^em1(IMPC)Mbp*	Intra-exon deletion	‌	mouse
*Champ1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Champ1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Champ1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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