Ncald | neurocalcin delta

GeneMGI:1196326Synonyms: D030020D09Rik, D15Ertd412e

Physiological systems

18 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Nervous system Vision/eye Behavior/neurological Skeleton Cardiovascular system

12 No significant impact

6 Not tested

Gene metrics:19Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
50Embryo tissues

Phenotypes

hyperactivity8 supporting datasetsNcaldtm1.1(KOMP)VlcghomozygoteEarly adult3.48x10-17 
decreased thigmotaxis6 supporting datasetsNcaldtm1.1(KOMP)VlcghomozygoteEarly adult1.96x10-6 
decreased bone mineral content2 supporting datasetsNcaldtm1.1(KOMP)VlcghomozygoteEarly adult4.78x10-9 
abnormal retina vasculature morphology1 supporting datasetNcaldtm1.1(KOMP)VlcghomozygoteEarly adult7.44x10-5 
decreased circulating free fatty acids level1 supporting datasetNcaldtm1.1(KOMP)VlcghomozygoteEarly adult4.33x10-5 
increased circulating alkaline phosphatase level1 supporting datasetNcaldtm1.1(KOMP)VlcghomozygoteEarly adult2.98x10-6 
decreased prepulse inhibition3 supporting datasetsNcaldtm1.1(KOMP)VlcghomozygoteEarly adult1.58x10-8 
impaired pupillary reflex1 supporting datasetNcaldtm1.1(KOMP)VlcghomozygoteEarly adult3.95x10-6 
mydriasis1 supporting datasetNcaldtm1.1(KOMP)VlcghomozygoteEarly adult6.26x10-11 
increased circulating insulin level1 supporting datasetNcaldtm1.1(KOMP)VlcghomozygoteEarly adult1.67x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ncaldtm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Ncaldtm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse

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