Hgsnat | heparan-alpha-glucosaminide N-acetyltransferase

GeneMGI:1196297Synonyms: D8Ertd354e, 9430010M12Rik, +1 more

Physiological systems

19 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Adipose tissue Growth/size/body region Limbs/digits/tail Respiratory system Behavior/neurological Skeleton Renal/urinary system

10 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:16Significant phenotypes

4Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



enlarged lymph nodes	1 supporting dataset	Hgsnat^em4(IMPC)Tcp	homozygote	Early adult	N/A ^*
abnormal cholesterol homeostasis	1 supporting dataset	Hgsnat^em4(IMPC)Tcp	homozygote	Early adult	8.26x10^-5
decreased exploration in new environment	1 supporting dataset	Hgsnat^em4(IMPC)Tcp	homozygote	Early adult	6.63x10^-5
abnormal lung morphology	1 supporting dataset	Hgsnat^em4(IMPC)Tcp	homozygote	Early adult	N/A ^*
increased circulating alkaline phosphatase level	1 supporting dataset	Hgsnat^em4(IMPC)Tcp	homozygote	Early adult	2.64x10^-5
decreased circulating serum albumin level	1 supporting dataset	Hgsnat^em4(IMPC)Tcp	homozygote	Early adult	7.86x10^-6
increased circulating phosphate level	1 supporting dataset	Hgsnat^em4(IMPC)Tcp	homozygote	Early adult	9.44x10^-5
increased circulating potassium level	1 supporting dataset	Hgsnat^em4(IMPC)Tcp	homozygote	Early adult	3.11x10^-7
decreased total body fat amount	2 supporting datasets	Hgsnat^em4(IMPC)Tcp	homozygote	Early adult	1.26x10^-11
enlarged urinary bladder	1 supporting dataset	Hgsnat^em4(IMPC)Tcp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Hgsnat.

Associated images

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Histopathology

There is no histopathology data found for Hgsnat.

IMPC related publications

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External links

No external links available for Hgsnat.

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*Hgsnat^em4(IMPC)Tcp*	Indel	‌	mouse
*Hgsnat^em7(IMPC)Tcp*	Intra-exon deletion	‌	mouse
*Hgsnat^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Hgsnat^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Hgsnat^{tm2e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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