Fubp1 | far upstream element (FUSE) binding protein 1

GeneMGI:1196294Synonyms: FBP, 9530027K12Rik, +2 more

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Immune system Integument Vision/eye Behavior/neurological Mortality/aging

16 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



decreased anxiety-related response	1 supporting dataset	Fubp1^em1(IMPC)Mbp	heterozygote	Early adult	4.81x10^-5
decreased locomotor activity	1 supporting dataset	Fubp1^em1(IMPC)Mbp	heterozygote	Early adult	3.43x10^-21
no spontaneous movement	1 supporting dataset	Fubp1^em1(IMPC)Mbp	heterozygote	E18.5	N/A ^*
abnormal behavior	1 supporting dataset	Fubp1^em1(IMPC)Mbp	heterozygote	Early adult	4.2x10^-8
abnormal retina morphology	1 supporting dataset	Fubp1^em1(IMPC)Mbp	heterozygote	Early adult	5.3x10^-5
preweaning lethality, complete penetrance	3 supporting datasets	Fubp1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
decreased thigmotaxis	2 supporting datasets	Fubp1^em1(IMPC)Mbp	heterozygote	Early adult	3.69x10^-8
abnormal skin morphology	1 supporting dataset	Fubp1^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
enlarged lymph nodes	1 supporting dataset	Fubp1^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
abnormal lymph node morphology	1 supporting dataset	Fubp1^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fubp1.

Associated images

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Histopathology

There is no histopathology data found for Fubp1.

IMPC related publications

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External links

No external links available for Fubp1.

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*Fubp1^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Fubp1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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