Tubgcp4 | tubulin, gamma complex component 4

GeneMGI:1196293Synonyms: D2Ertd435e, 4932441P04Rik

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Integument Behavior/neurological Mortality/aging

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal vibrissa morphology1 supporting datasetTubgcp4em1(IMPC)JheterozygoteEarly adult4.96x10-9 
hyperactivity5 supporting datasetsTubgcp4em1(IMPC)JheterozygoteEarly adult1.97x10-5 
preweaning lethality, complete penetrance1 supporting datasetTubgcp4em1(IMPC)JhomozygoteEarly adultN/A * 
absent vibrissae1 supporting datasetTubgcp4em1(IMPC)JheterozygoteEarly adult1.26x10-6 
embryonic lethality prior to organogenesis1 supporting datasetTubgcp4em1(IMPC)JhomozygoteE9.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tubgcp4em1(IMPC)JExon Deletionmouse
Tubgcp4tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Tubgcp4tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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