Spice1 | spindle and centriole associated protein 1

GeneMGI:1196252Synonyms: Ccdc52, D16Ertd480e

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Hematopoietic system

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Phy. System:



increased circulating alkaline phosphatase level	1 supporting dataset	Spice1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	3.86x10^-7
increased red blood cell distribution width	1 supporting dataset	Spice1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.19x10^-6
improved glucose tolerance	1 supporting dataset	Spice1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	5.51x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Spice1.

Associated images

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Histopathology

There is no histopathology data found for Spice1.

IMPC related publications

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External links

No external links available for Spice1.

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*Spice1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Spice1^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Spice1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

My Genes