Casz1 | castor zinc finger 1

GeneMGI:1196251Synonyms: 2410019P08Rik, Cst, +2 more

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Vision/eye Mortality/aging

17 No significant impact

5 Not tested

Gene metrics:2Significant phenotypes
1Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues

Phenotypes

preweaning lethality, complete penetrance1 supporting datasetCasz1tm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
persistence of hyaloid vascular system1 supporting datasetCasz1tm1b(EUCOMM)HmguheterozygoteEarly adult2x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Casz1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Casz1tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Casz1tm1c(EUCOMM)HmguWild type floxed exon (post-Flp)mouse
Casz1tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

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