Tcaim | T cell activation inhibitor, mitochondrial

GeneMGI:1196217Synonyms: D9Ertd402e, LOC382117

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Hematopoietic system

15 No significant impact

6 Not tested

Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
0Embryo tissues

Phenotypes

increased neutrophil cell number1 supporting datasetTcaimtm1b(EUCOMM)WtsihomozygoteEarly adult4.34x10-5 
increased circulating cholesterol level1 supporting datasetTcaimtm1b(EUCOMM)WtsihomozygoteEarly adult8.07x10-5 
decreased lymphocyte cell number1 supporting datasetTcaimtm1b(EUCOMM)WtsihomozygoteEarly adult2.61x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tcaimtm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Tcaimtm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Tcaimtm1e(EUCOMM)HmguTargeted, non-conditional allelees cell
Tcaimtm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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