Tcaim | T cell activation inhibitor, mitochondrial

GeneMGI:1196217Synonyms: D9Ertd402e, LOC382117

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Hematopoietic system

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased neutrophil cell number	1 supporting dataset	Tcaim^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	4.34x10^-5
increased circulating cholesterol level	1 supporting dataset	Tcaim^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	8.07x10^-5
decreased lymphocyte cell number	1 supporting dataset	Tcaim^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.61x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tcaim.

Associated images

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Histopathology

There is no histopathology data found for Tcaim.

IMPC related publications

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External links

No external links available for Tcaim.

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*Tcaim^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Tcaim^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Tcaim^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Tcaim^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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