Cbx4 | chromobox 4
Physiological systems
19 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Adipose tissue Embryo Growth/size/body region Behavior/neurological Mortality/aging
14 No significant impact
5 Not tested
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:42Adult tissues
50Embryo tissues
abnormal embryo size | 1 supporting dataset | Cbx4tm1.1(KOMP)Vlcg | heterozygote | E15.5 | N/A * | ||
hyperactivity | 1 supporting dataset | Cbx4tm1.1(KOMP)Vlcg | heterozygote | Early adult | 7.43x10-7 | ||
increased total body fat amount | 1 supporting dataset | Cbx4tm1.1(KOMP)Vlcg | heterozygote | Early adult | 1.63x10-5 | ||
abnormal embryo size | 1 supporting dataset | Cbx4tm1.1(KOMP)Vlcg | homozygote | E15.5 | N/A * | ||
preweaning lethality, complete penetrance | 3 supporting datasets | Cbx4tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
decreased lean body mass | 1 supporting dataset | Cbx4tm1.1(KOMP)Vlcg | heterozygote | Early adult | 2.81x10-7 |
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External links
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Cbx4tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | es cell mouse |
Cbx4tm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
Cbx4tm2e(EUCOMM)Hmgu | Targeted, non-conditional allele | | es cell |
Cbx4tm380190(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |