Ilk | integrin linked kinase
Physiological systems
19 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Embryo Growth/size/body region Vision/eye Behavior/neurological Mortality/aging
13 No significant impact
5 Not tested
Data collections
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
25Embryo tissues
| increased vertical activity | 1 supporting dataset | Ilktm1.1(KOMP)Vlcg | heterozygote | Early adult | 7.57x10-6 | ||
| abnormal embryo size | 1 supporting dataset | Ilktm1.1(KOMP)Vlcg | heterozygote | E9.5 | N/A * | ||
| hyperactivity | 5 supporting datasets | Ilktm1.1(KOMP)Vlcg | heterozygote | Early adult | 8.48x10-7 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Ilktm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| abnormal lens morphology | 1 supporting dataset | Ilktm1.1(KOMP)Vlcg | heterozygote | Early adult | 3.81x10-5 | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Ilktm1.1(KOMP)Vlcg | homozygote | E9.5 | N/A * | ||
| increased circulating phosphate level | 1 supporting dataset | Ilktm1.1(KOMP)Vlcg | heterozygote | Early adult | 1x10-5 |
| | | | | | | | | | |
External links
No external links available for Ilk.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Ilktm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Ilktm1(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |
| Ilktm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |