Dsc3 | desmocollin 3
Physiological systems
16 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Nervous system Vision/eye Behavior/neurological Mortality/aging
11 No significant impact
8 Not tested
Gene metrics:6Significant phenotypes
2Associated diseases
Expression examined in:46Adult tissues
0Embryo tissues
| decreased fasting circulating glucose level | 1 supporting dataset | Dsc3tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 1.81x10-11 | ||
| hyperactivity | 1 supporting dataset | Dsc3tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 5.05x10-6 | ||
| abnormal behavior | 1 supporting dataset | Dsc3tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 3.91x10-5 | ||
| decreased thigmotaxis | 1 supporting dataset | Dsc3tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 3.91x10-5 | ||
| absent optic nerve | 1 supporting dataset | Dsc3tm1b(EUCOMM)Wtsi | heterozygote | Early adult | N/A * | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Dsc3tm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * |
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External links
No external links available for Dsc3.
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| Dsc3tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Dsc3tm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Dsc3tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | es cell |