Crx | cone-rod homeobox

GeneMGI:1194883Synonyms: Crx1

Physiological systems

21 / 24 physiological systems tested

11 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological Cardiovascular system Renal/urinary system

10 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:15Significant phenotypes
5Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged urinary bladder1 supporting datasetCrxem1(IMPC)CcpczhomozygoteEarly adultN/A * 
increased NK cell number1 supporting datasetCrxem1(IMPC)CcpczhomozygoteEarly adult6.84x10-5 
abnormal retina morphology1 supporting datasetCrxem1(IMPC)CcpczhomozygoteEarly adult1.59x10-9 
abnormal skin morphology1 supporting datasetCrxem1(IMPC)CcpczhomozygoteEarly adultN/A * 
enlarged heart1 supporting datasetCrxem1(IMPC)CcpczhomozygoteEarly adultN/A * 
small thymus1 supporting datasetCrxem1(IMPC)CcpczhomozygoteEarly adultN/A * 
increased fasting circulating glucose level1 supporting datasetCrxem1(IMPC)CcpczhomozygoteEarly adult3.56x10-7 
abnormal seminal vesicle morphology1 supporting datasetCrxem1(IMPC)CcpczhomozygoteEarly adultN/A * 
decreased exploration in new environment1 supporting datasetCrxem1(IMPC)CcpczhomozygoteEarly adult2.52x10-7 
abnormal thymus morphology2 supporting datasetsCrxem1(IMPC)CcpczhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Crxem1(IMPC)CcpczExon Deletionmouse

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