Kcnj10 | potassium inwardly-rectifying channel, subfamily J, member 10

GeneMGI:1194504Synonyms: Kir1.2, BIR10, +2 more

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Immune system Hematopoietic system Behavior/neurological Mortality/aging

15 No significant impact

5 Not tested

Gene metrics:6Significant phenotypes
4Associated diseases
Expression examined in:46Adult tissues
0Embryo tissues

Phenotypes

tremors1 supporting datasetKcnj10tm1b(KOMP)WtsiheterozygoteEarly adult9.22x10-5 
decreased exploration in new environment1 supporting datasetKcnj10tm1b(KOMP)WtsiheterozygoteEarly adult7.49x10-5 
increased startle reflex1 supporting datasetKcnj10tm1b(KOMP)WtsiheterozygoteEarly adult4.76x10-9 
decreased basophil cell number1 supporting datasetKcnj10tm1b(KOMP)WtsiheterozygoteEarly adult6.14x10-5 
decreased mean platelet volume1 supporting datasetKcnj10tm1b(KOMP)WtsiheterozygoteEarly adult6.53x10-26 
preweaning lethality, complete penetrance1 supporting datasetKcnj10tm1b(KOMP)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Kcnj10tm1(EGFP_CreERT2)WtsiReporter-tagged deletion allele (with selection cassette)es cell
Kcnj10tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Kcnj10tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Kcnj10tm1e(KOMP)WtsiTargeted, non-conditional allelees cell

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