Ablim1 | actin-binding LIM protein 1

GeneMGI:1194500Synonyms: abLIM-L, abLIM-M, +6 more

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Vision/eye Behavior/neurological Skeleton Cardiovascular system

14 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased circulating potassium level	1 supporting dataset	Ablim1^tm1H	homozygote	Early adult	2.22x10^-6
abnormal bone structure	1 supporting dataset	Ablim1^tm1H	homozygote	Early adult	1.71x10^-6
decreased thermal nociceptive threshold	1 supporting dataset	Ablim1^tm1H	homozygote	Early adult	8.63x10^-9
increased bone mineral density	1 supporting dataset	Ablim1^tm1H	homozygote	Early adult	9.18x10^-5
decreased circulating glucose level	1 supporting dataset	Ablim1^tm1H	homozygote	Early adult	2.85x10^-6
increased lean body mass	2 supporting datasets	Ablim1^tm1H	homozygote	Early adult	2.27x10^-6
increased bone mineral content	1 supporting dataset	Ablim1^tm1H	homozygote	Early adult	1.29x10^-5
abnormal bone mineralization	1 supporting dataset	Ablim1^tm1H	homozygote	Early adult	6.4x10^-6
eye hemorrhage	1 supporting dataset	Ablim1^tm1H	homozygote	Early adult	8.43x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ablim1.

Associated images

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Histopathology

There is no histopathology data found for Ablim1.

IMPC related publications

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External links

No external links available for Ablim1.

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*Ablim1^tm1H*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Ablim1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Ablim1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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