Asic2 | acid-sensing ion channel 2

GeneMGI:1100867Synonyms: BNC1, BNaC1a, +2 more

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Immune system Hematopoietic system Behavior/neurological Renal/urinary system

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal kidney morphology1 supporting datasetAsic2em1(IMPC)MbphomozygoteEarly adultN/A * 
small spleen1 supporting datasetAsic2em1(IMPC)MbphomozygoteEarly adultN/A * 
increased freezing behavior1 supporting datasetAsic2em1(IMPC)MbphomozygoteEarly adult1.07x10-13 
small kidney1 supporting datasetAsic2em1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Asic2em1(IMPC)MbpExon Deletionmouse
Asic2tm33657(L1L2_gt0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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