Kpna4 | karyopherin subunit alpha 4

GeneMGI:1100848Synonyms: IPOA3, 1110058D08Rik, +1 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Behavior/neurological Skeleton

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal vocalization	1 supporting dataset	Kpna4^em1(IMPC)J	homozygote	Early adult	2.94x10^-10
increased bone mineral density	1 supporting dataset	Kpna4^em1(IMPC)J	homozygote	Early adult	1.25x10^-5
increased startle reflex	1 supporting dataset	Kpna4^em1(IMPC)J	homozygote	Early adult	2.04x10^-11

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Kpna4.

Associated images

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Histopathology

There is no histopathology data found for Kpna4.

IMPC related publications

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External links

No external links available for Kpna4.

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*Kpna4^em1(IMPC)J*	Exon Deletion	‌	mouse
*Kpna4^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Kpna4^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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