Bub1 | BUB1, mitotic checkpoint serine/threonine kinase

GeneMGI:1100510Synonyms: Bub1a, D2Xrf87

Physiological systems

18 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Mortality/aging

17 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

3Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Life Stage:



preweaning lethality, complete penetrance	3 supporting datasets	Bub1^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
embryonic lethality prior to organogenesis	1 supporting dataset	Bub1^em1(IMPC)Bay	homozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Bub1.

Associated images

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Histopathology

There is no histopathology data found for Bub1.

IMPC related publications

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External links

No external links available for Bub1.

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*Bub1^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Bub1^{tm295550(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Bub1^{tm35125(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes