Fmo3 | flavin containing monooxygenase 3

Physiological systems

20 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological Renal/urinary system

12 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



abnormal eye morphology	2 supporting datasets	Fmo3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
hyperactivity	1 supporting dataset	Fmo3^em1(IMPC)Mbp	homozygote	Early adult	1.79x10^-5
enlarged spleen	1 supporting dataset	Fmo3^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal eye morphology	1 supporting dataset	Fmo3^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal ovary morphology	1 supporting dataset	Fmo3^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
enlarged ovary	1 supporting dataset	Fmo3^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal kidney morphology	2 supporting datasets	Fmo3^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
enlarged lymph nodes	1 supporting dataset	Fmo3^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Fmo3^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
anophthalmia	1 supporting dataset	Fmo3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fmo3.

Associated images

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Histopathology

There is no histopathology data found for Fmo3.

IMPC related publications

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External links

No external links available for Fmo3.

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*Fmo3^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Fmo3^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Fmo3^{tm42619(L1L2_gt1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes