Skic2 | SKI2 subunit of superkiller complex
Physiological systems
20 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Homeostasis/metabolism Mortality/aging
18 No significant impact
4 Not tested
Data collections
Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:50Adult tissues
62Embryo tissues
| embryonic lethality prior to organogenesis | 1 supporting dataset | Skic2tm2b(EUCOMM)Wtsi | homozygote | E9.5 | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Skic2tm2b(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| increased circulating total protein level | 1 supporting dataset | Skic2tm2b(EUCOMM)Wtsi | heterozygote | Early adult | 8.68x10-5 | ||
| decreased circulating chloride level | 1 supporting dataset | Skic2tm2b(EUCOMM)Wtsi | heterozygote | Early adult | 5.66x10-5 |
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External links
No external links available for Skic2.
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| Skic2tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Skic2tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Skic2tm2a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Skic2tm2b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |