Hip1 | huntingtin interacting protein 1

GeneMGI:1099804Synonyms: HIP-1, A930014B11Rik, +2 more

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Vision/eye Behavior/neurological Skeleton

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased locomotor activity	7 supporting datasets	Hip1^{em1(IMPC)Hmgu}	homozygote	Early adult	5.55x10^-35
hyperactivity	3 supporting datasets	Hip1^{em1(IMPC)Hmgu}	homozygote	Early adult	1.63x10^-12
abnormal gait	1 supporting dataset	Hip1^{em1(IMPC)Hmgu}	homozygote	Early adult	5.03x10^-8
cornea opacity	1 supporting dataset	Hip1^{em1(IMPC)Hmgu}	homozygote	Early adult	4.12x10^-6
abnormal vertebrae morphology	1 supporting dataset	Hip1^{em1(IMPC)Hmgu}	homozygote	Early adult	1.22x10^-8
decreased circulating creatinine level	1 supporting dataset	Hip1^{em1(IMPC)Hmgu}	homozygote	Early adult	3.55x10^-15
decreased vertical activity	1 supporting dataset	Hip1^{em1(IMPC)Hmgu}	homozygote	Early adult	7.11x10^-17
abnormal cornea morphology	1 supporting dataset	Hip1^{em1(IMPC)Hmgu}	homozygote	Early adult	3.11x10^-5
increased bone mineral content	1 supporting dataset	Hip1^{em1(IMPC)Hmgu}	homozygote	Early adult	0
decreased body length	1 supporting dataset	Hip1^{em1(IMPC)Hmgu}	homozygote	Early adult	4.04x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Hip1.

Associated images

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Histopathology

There is no histopathology data found for Hip1.

IMPC related publications

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External links

No external links available for Hip1.

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*Hip1^{em1(IMPC)Hmgu}*	Exon Deletion	‌	mouse
*Hip1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Hip1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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