Ccl25 | C-C motif chemokine ligand 25

GeneMGI:1099448Synonyms: TECK, CKb15, +1 more

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Growth/size/body region Hematopoietic system Behavior/neurological

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased fasting circulating glucose level1 supporting datasetCcl25em1(IMPC)HhomozygoteEarly adult7.22x10-5 
increased grip strength1 supporting datasetCcl25em1(IMPC)HhomozygoteLate adult2.86x10-5 
increased spleen weight1 supporting datasetCcl25em1(IMPC)HhomozygoteLate adult9.56x10-6 
increased circulating alanine transaminase level1 supporting datasetCcl25em1(IMPC)HhomozygoteLate adult1.05x10-10 
enlarged spleen1 supporting datasetCcl25em1(IMPC)HhomozygoteLate adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ccl25em1(IMPC)HExon Deletionmouse
Ccl25em2(IMPC)HExon Deletionmouse
Ccl25tm1.1(EGFP/cre/ERT2)WtsiReporter-tagged deletion allele (post Cre, with no selection cassette)es cell
mouse
Ccl25tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Ccl25tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell
Ccl25tm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Ccl25tm2e(EUCOMM)HmguTargeted, non-conditional allelees cell

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