Atxn3 | ataxin 3

GeneMGI:1099442Synonyms: Atx3, Sca3, +4 more

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

5Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased circulating fructosamine level	1 supporting dataset	Atxn3^{tm1a(KOMP)Wtsi}	homozygote	Early adult	6.98x10^-5
increased circulating aspartate transaminase level	1 supporting dataset	Atxn3^{tm1a(KOMP)Wtsi}	homozygote	Early adult	2.62x10^-5
increased anti-nuclear antigen antibody level	4 supporting datasets	Atxn3^{tm1a(KOMP)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Atxn3.

Associated images

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Histopathology

There is no histopathology data found for Atxn3.

IMPC related publications

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External links

No external links available for Atxn3.

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*Atxn3^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Atxn3^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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