Slc46a1 | solute carrier family 46, member 1
Physiological systems
17 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Integument Behavior/neurological
14 No significant impact
7 Not tested
Data collections
Gene metrics:7Significant phenotypes
2Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues
| abnormal coat appearance | 1 supporting dataset | Slc46a1tm1b(KOMP)Mbp | heterozygote | Early adult | 2.9x10-6 | ||
| decreased locomotor activity | 2 supporting datasets | Slc46a1tm1b(KOMP)Mbp | homozygote | Early adult | 1.62x10-5 | ||
| decreased circulating glucose level | 1 supporting dataset | Slc46a1tm1b(KOMP)Mbp | heterozygote | Early adult | 3.24x10-9 | ||
| increased circulating potassium level | 1 supporting dataset | Slc46a1tm1b(KOMP)Mbp | heterozygote | Early adult | 4.6x10-9 | ||
| increased circulating aspartate transaminase level | 1 supporting dataset | Slc46a1tm1b(KOMP)Mbp | heterozygote | Early adult | 9.5x10-7 | ||
| decreased circulating iron level | 1 supporting dataset | Slc46a1tm1b(KOMP)Mbp | heterozygote | Early adult | 4.14x10-7 | ||
| increased circulating bilirubin level | 1 supporting dataset | Slc46a1tm1b(KOMP)Mbp | heterozygote | Early adult | 6.91x10-7 |
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External links
No external links available for Slc46a1.
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| Slc46a1tm1a(KOMP)Mbp | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Slc46a1tm1b(KOMP)Mbp | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Slc46a1tm1e(KOMP)Mbp | Targeted, non-conditional allele | | ES Cell |