Eif2a | eukaryotic translation initiation factor 2A

GeneMGI:1098684Synonyms: D3Ertd194e

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Immune system Integument Growth/size/body region Hematopoietic system Behavior/neurological

15 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased exploration in new environment	1 supporting dataset	Eif2a^em1(IMPC)Mbp	homozygote	Early adult	1.97x10^-5
increased mean platelet volume	1 supporting dataset	Eif2a^em1(IMPC)Mbp	homozygote	Early adult	2.06x10^-5
enlarged spleen	1 supporting dataset	Eif2a^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Eif2a^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Eif2a^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Eif2a.

Associated images

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Histopathology

There is no histopathology data found for Eif2a.

IMPC related publications

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External links

No external links available for Eif2a.

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*Eif2a^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Eif2a^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Eif2a^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Eif2a^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Eif2a^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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