Anapc4 | anaphase promoting complex subunit 4

GeneMGI:1098673Synonyms: 2610306D21Rik, APC4, +1 more

Physiological systems

20 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Mortality/aging

19 No significant impact

4 Not tested

Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
62Embryo tissues

Phenotypes

preweaning lethality, complete penetrance3 supporting datasetsAnapc4tm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
embryonic lethality prior to organogenesis1 supporting datasetAnapc4tm1b(EUCOMM)WtsihomozygoteE9.5N/A * 
embryonic lethality prior to tooth bud stage1 supporting datasetAnapc4tm1b(EUCOMM)WtsihomozygoteE12.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Anapc4tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Anapc4tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Anapc4tm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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