Tmem222 | transmembrane protein 222

GeneMGI:1098568Synonyms: 5730406H10Rik, D4Ertd196e

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Nervous system Vision/eye Behavior/neurological Mortality/aging

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

2Associated diseases

Expression examined in:49Adult tissues

50Embryo tissues

Phenotypes

Zygosity:

Phy. System:



impaired pupillary reflex	1 supporting dataset	Tmem222^{tm1b(KOMP)Mbp}	heterozygote	Early adult	7.29x10^-7
decreased prepulse inhibition	3 supporting datasets	Tmem222^{tm1b(KOMP)Mbp}	heterozygote	Early adult	1.18x10^-5
preweaning lethality, incomplete penetrance	1 supporting dataset	Tmem222^{tm1b(KOMP)Mbp}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tmem222.

Associated images

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Histopathology

There is no histopathology data found for Tmem222.

IMPC related publications

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External links

No external links available for Tmem222.

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*Tmem222^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Tmem222^{tm1b(KOMP)Mbp}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Tmem222^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	ES Cell

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