Impact | impact, RWD domain protein

GeneMGI:1098233Synonyms: E430016J11Rik

Physiological systems

22 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Growth/size/body region Respiratory system Cardiovascular system

17 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal lung morphology	1 supporting dataset	Impact^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal QT variability	1 supporting dataset	Impact^{em1(IMPC)Ccpcz}	homozygote	Early adult	8.6x10^-7
prolonged RR interval	1 supporting dataset	Impact^{em1(IMPC)Ccpcz}	homozygote	Early adult	3.51x10^-6
enlarged lung	1 supporting dataset	Impact^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged lymph nodes	1 supporting dataset	Impact^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
increased fasting circulating glucose level	1 supporting dataset	Impact^{em1(IMPC)Ccpcz}	homozygote	Early adult	5.07x10^-5
cardiovascular system phenotype	1 supporting dataset	Impact^{em1(IMPC)Ccpcz}	homozygote	Early adult	5.05x10^-7
abnormal lymph node morphology	1 supporting dataset	Impact^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
increased circulating HDL cholesterol level	1 supporting dataset	Impact^{em1(IMPC)Ccpcz}	homozygote	Early adult	9.96x10^-5
abnormal sinus arrhythmia	1 supporting dataset	Impact^{em1(IMPC)Ccpcz}	homozygote	Early adult	3.12x10^-21

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Impact.

Associated images

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Histopathology

There is no histopathology data found for Impact.

IMPC related publications

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External links

No external links available for Impact.

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*Impact^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Impact^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Impact^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Impact^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Impact^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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