Polr1a | polymerase (RNA) I polypeptide A

GeneMGI:1096397Synonyms: 2900087K15Rik, 3010014K16Rik, +4 more

Physiological systems

16 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Vision/eye Mortality/aging

14 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

3Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal retina outer nuclear layer morphology	1 supporting dataset	Polr1a^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.99x10^-5
preweaning lethality, complete penetrance	3 supporting datasets	Polr1a^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Polr1a.

Associated images

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Histopathology

There is no histopathology data found for Polr1a.

IMPC related publications

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External links

No external links available for Polr1a.

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*Polr1a^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Polr1a^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Polr1a^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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