Ampd3 | adenosine monophosphate deaminase 3

GeneMGI:1096344

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological

14 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

2Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased circulating potassium level	1 supporting dataset	Ampd3^{tm2a(KOMP)Wtsi}	homozygote	Early adult	2.55x10^-9
decreased circulating glucose level	1 supporting dataset	Ampd3^{tm2a(KOMP)Wtsi}	homozygote	Early adult	1.04x10^-6
abnormal behavior	3 supporting datasets	Ampd3^{tm2a(KOMP)Wtsi}	homozygote	Early adult	3.97x10^-9
increased leukocyte cell number	1 supporting dataset	Ampd3^{tm2a(KOMP)Wtsi}	homozygote	Early adult	4.63x10^-7
increased lean body mass	1 supporting dataset	Ampd3^{tm2a(KOMP)Wtsi}	homozygote	Early adult	7.9x10^-5
decreased circulating magnesium level	1 supporting dataset	Ampd3^{tm2a(KOMP)Wtsi}	homozygote	Early adult	1.08x10^-5
decreased total body fat amount	1 supporting dataset	Ampd3^{tm2a(KOMP)Wtsi}	homozygote	Early adult	1.12x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ampd3.

Associated images

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Histopathology

There is no histopathology data found for Ampd3.

IMPC related publications

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External links

No external links available for Ampd3.

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*Ampd3^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Ampd3^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Ampd3^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Ampd3^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Ampd3^{tm42333(L1L2_Pgk_PM)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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