Serpinb5 | serine (or cysteine) peptidase inhibitor, clade B, member 5

GeneMGI:109579Synonyms: Spi7, ovalbumin, +2 more

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

50Embryo tissues

Phenotypes

Phy. System:



increased circulating cholesterol level	1 supporting dataset	Serpinb5^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.06x10^-7
impaired righting response	1 supporting dataset	Serpinb5^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.49x10^-6
abnormal sleep behavior	1 supporting dataset	Serpinb5^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.6x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Serpinb5.

Associated images

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Histopathology

There is no histopathology data found for Serpinb5.

IMPC related publications

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External links

No external links available for Serpinb5.

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*Serpinb5^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Serpinb5^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Serpinb5^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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