Tuft1 | tuftelin 1

GeneMGI:109572

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Integument Vision/eye

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal coat appearance	6 supporting datasets	Tuft1^{tm1a(KOMP)Wtsi}	homozygote	Early adult	8.76x10^-21
decreased circulating alkaline phosphatase level	1 supporting dataset	Tuft1^{tm1a(KOMP)Wtsi}	homozygote	Early adult	3.37x10^-5
improved glucose tolerance	1 supporting dataset	Tuft1^{tm1a(KOMP)Wtsi}	homozygote	Early adult	6.05x10^-6
abnormal vibrissa morphology	1 supporting dataset	Tuft1^{tm1a(KOMP)Wtsi}	homozygote	Early adult	6.9x10^-6
abnormal eyelid morphology	1 supporting dataset	Tuft1^{tm1a(KOMP)Wtsi}	homozygote	Early adult	3.6x10^-5
decreased circulating HDL cholesterol level	1 supporting dataset	Tuft1^{tm1a(KOMP)Wtsi}	homozygote	Early adult	5.35x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tuft1.

Associated images

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Histopathology

There is no histopathology data found for Tuft1.

IMPC related publications

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External links

No external links available for Tuft1.

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*Tuft1^{tm115823(L1L2_Pgk_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Tuft1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Tuft1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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