Fmnl3 | formin-like 3

GeneMGI:109569Synonyms: 2700073B04Rik, Wbp3

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Integument Behavior/neurological Mortality/aging

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:49Adult tissues

62Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



preweaning lethality, incomplete penetrance	2 supporting datasets	Fmnl3^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
unresponsive to tactile stimuli	1 supporting dataset	Fmnl3^{tm1b(KOMP)Wtsi}	homozygote	E18.5	N/A ^*
unresponsive to tactile stimuli	1 supporting dataset	Fmnl3^{tm1b(KOMP)Wtsi}	heterozygote	E18.5	N/A ^*
abnormal skin coloration	1 supporting dataset	Fmnl3^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	4.34x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fmnl3.

Associated images

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Histopathology

There is no histopathology data found for Fmnl3.

IMPC related publications

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External links

No external links available for Fmnl3.

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*Fmnl3^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Fmnl3^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Fmnl3^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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