Crybg1 | crystallin beta-gamma domain containing 1
Physiological systems
19 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Adipose tissue Nervous system Vision/eye Behavior/neurological Mortality/aging
13 No significant impact
5 Not tested
Data collections
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
29Embryo tissues
| preweaning lethality, complete penetrance | 3 supporting datasets | Crybg1tm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Crybg1tm1b(KOMP)Wtsi | homozygote | E12.5 | N/A * | ||
| decreased prepulse inhibition | 6 supporting datasets | Crybg1tm1b(KOMP)Wtsi | heterozygote | Early adult | 3.94x10-16 | ||
| increased blood urea nitrogen level | 1 supporting dataset | Crybg1tm1b(KOMP)Wtsi | heterozygote | Early adult | 3.41x10-5 | ||
| decreased exploration in new environment | 1 supporting dataset | Crybg1tm1b(KOMP)Wtsi | heterozygote | Early adult | 2.49x10-5 | ||
| abnormal eye morphology | 1 supporting dataset | Crybg1tm1b(KOMP)Wtsi | heterozygote | Early adult | N/A * | ||
| decreased total body fat amount | 1 supporting dataset | Crybg1tm1b(KOMP)Wtsi | heterozygote | Early adult | 9.03x10-5 |
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External links
No external links available for Crybg1.
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| Crybg1tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Crybg1tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Crybg1tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |