Mfng | MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

GeneMGI:1095404Synonyms: manic fringe

Physiological systems

22 / 24 physiological systems tested

10 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological Skeleton Cardiovascular system

12 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:16Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



enlarged heart	1 supporting dataset	Mfng^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal ovary morphology	1 supporting dataset	Mfng^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Mfng^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal thymus morphology	1 supporting dataset	Mfng^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal eye morphology	1 supporting dataset	Mfng^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
hydrometra	1 supporting dataset	Mfng^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
kyphosis	1 supporting dataset	Mfng^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.53x10^-6
decreased startle reflex	1 supporting dataset	Mfng^{em1(IMPC)Ccpcz}	homozygote	Early adult	6.38x10^-8
decreased locomotor activity	2 supporting datasets	Mfng^{em1(IMPC)Ccpcz}	homozygote	Early adult	8.76x10^-6
enlarged thymus	1 supporting dataset	Mfng^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mfng.

Associated images

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Histopathology

There is no histopathology data found for Mfng.

IMPC related publications

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External links

No external links available for Mfng.

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*Mfng^{em1(IMPC)Ccpcz}*	Inter-exon deletion	‌	mouse
*Mfng^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Mfng^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell
*Mfng^{tm40124(L1L2_st0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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