Col16a1 | collagen, type XVI, alpha 1

GeneMGI:1095396Synonyms: 2700007F12Rik, A530052M23Rik, +1 more

Physiological systems

16 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Vision/eye Behavior/neurological

13 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased grip strength1 supporting datasetCol16a1em1(IMPC)JhomozygoteEarly adult7.52x10-6 
decreased circulating calcium level1 supporting datasetCol16a1em1(IMPC)JhomozygoteEarly adult4.73x10-14 
decreased circulating total protein level1 supporting datasetCol16a1em1(IMPC)JhomozygoteEarly adult3.74x10-11 
cataract1 supporting datasetCol16a1em1(IMPC)JhomozygoteEarly adult7.01x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Col16a1em1(IMPC)JExon Deletionmouse
Col16a1tm352048(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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