Cdc37 | cell division cycle 37

GeneMGI:109531Synonyms: p50Cdc37

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological Mortality/aging

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

hyperactivity4 supporting datasetsCdc37em1(IMPC)JheterozygoteEarly adult2.31x10-5 
embryonic lethality prior to organogenesis1 supporting datasetCdc37em1(IMPC)JhomozygoteE9.5N/A * 
increased circulating alkaline phosphatase level1 supporting datasetCdc37em1(IMPC)JheterozygoteEarly adult8.2x10-6 
increased startle reflex1 supporting datasetCdc37em1(IMPC)JheterozygoteEarly adult6.69x10-7 
preweaning lethality, complete penetrance1 supporting datasetCdc37em1(IMPC)JhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cdc37em1(IMPC)JExon Deletionmouse
Cdc37tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Cdc37tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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