Msh3 | mutS homolog 3

GeneMGI:109519Synonyms: Rep3, D13Em1, +1 more

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Integument Growth/size/body region Vision/eye Renal/urinary system

16 No significant impact

4 Not tested

Gene metrics:5Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

cataract1 supporting datasetMsh3em1(IMPC)MbphomozygoteEarly adult6.35x10-5 
abnormal skin morphology1 supporting datasetMsh3em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal vitreous body morphology1 supporting datasetMsh3em1(IMPC)MbphomozygoteEarly adult5.99x10-5 
enlarged kidney1 supporting datasetMsh3em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal kidney morphology1 supporting datasetMsh3em1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Msh3em1(IMPC)MbpExon Deletionmouse

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