Sms | spermine synthase
Physiological systems
20 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Growth/size/body region Skeleton
16 No significant impact
4 Not tested
Data collections
Gene metrics:9Significant phenotypes
2Associated diseases
Expression examined in:90Adult tissues
0Embryo tissues
| increased circulating sodium level | 1 supporting dataset | Smstm1a(EUCOMM)Wtsi | hemizygote | Early adult | 6.43x10-5 | ||
| decreased body weight | 5 supporting datasets | Smstm1a(EUCOMM)Wtsi | hemizygote | Early adult | 1.55x10-15 | ||
| male infertility | 1 supporting dataset | Smstm1a(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| increased blood urea nitrogen level | 1 supporting dataset | Smstm1a(EUCOMM)Wtsi | hemizygote | Early adult | 2.72x10-6 | ||
| increased circulating amylase level | 1 supporting dataset | Smstm1a(EUCOMM)Wtsi | hemizygote | Early adult | 1.21x10-6 | ||
| decreased circulating glucose level | 1 supporting dataset | Smstm1a(EUCOMM)Wtsi | hemizygote | Early adult | 6.75x10-6 | ||
| decreased bone mineral density | 1 supporting dataset | Smstm1a(EUCOMM)Wtsi | hemizygote | Early adult | 2.49x10-5 | ||
| decreased circulating potassium level | 1 supporting dataset | Smstm1a(EUCOMM)Wtsi | hemizygote | Early adult | 5.79x10-6 |
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External links
No external links available for Sms.
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| Smstm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Smstm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |