Lum | lumican

GeneMGI:109347Synonyms: SLRR2D, Ldc

Physiological systems

22 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Limbs/digits/tail Mortality/aging

19 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:74Adult tissues

51Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal tail morphology	1 supporting dataset	Lum^{tm1.1(KOMP)Vlcg}	homozygote	E15.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Lum^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
increased circulating aspartate transaminase level	1 supporting dataset	Lum^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	8.2x10^-8
increased circulating alanine transaminase level	1 supporting dataset	Lum^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	1.68x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Lum.

Associated images

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Histopathology

There is no histopathology data found for Lum.

IMPC related publications

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External links

No external links available for Lum.

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*Lum^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Lum^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse

My Genes