Ctr9 | CTR9 homolog, Paf1/RNA polymerase II complex component

GeneMGI:109345Synonyms: Sh2bp1, Tsbp, +1 more

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Mortality/aging

16 No significant impact

6 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

prenatal lethality prior to heart atrial septation1 supporting datasetCtr9tm1b(EUCOMM)WtsihomozygoteE15.5N/A * 
preweaning lethality, complete penetrance1 supporting datasetCtr9tm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
embryonic lethality prior to organogenesis1 supporting datasetCtr9tm1b(EUCOMM)WtsihomozygoteE9.5N/A * 
increased circulating alanine transaminase level1 supporting datasetCtr9tm1b(EUCOMM)WtsiheterozygoteEarly adult5.25x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ctr9tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Ctr9tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Ctr9tm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell
Ctr9tm42435(pL1L2_GT0_DelLacZ_bsd)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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