Etv6 | ets variant 6

GeneMGI:109336Synonyms: translocation-ets-leukemia, Tel

Physiological systems

18 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Growth/size/body region Liver/biliary system Hematopoietic system Skeleton Cardiovascular system Mortality/aging Renal/urinary system

9 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:20Significant phenotypes

9Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



decreased circulating HDL cholesterol level	1 supporting dataset	Etv6^{em1(IMPC)Rbrc}	heterozygote	Early adult	5.76x10^-8
decreased bone mineral density	1 supporting dataset	Etv6^{em1(IMPC)Rbrc}	heterozygote	Early adult	3.53x10^-6
small liver	2 supporting datasets	Etv6^{em1(IMPC)Rbrc}	heterozygote	Late adult	N/A ^*
increased spleen weight	1 supporting dataset	Etv6^{em1(IMPC)Rbrc}	heterozygote	Late adult	2.26x10^-6
decreased circulating serum albumin level	1 supporting dataset	Etv6^{em1(IMPC)Rbrc}	heterozygote	Early adult	4.34x10^-7
increased heart atrium size	2 supporting datasets	Etv6^{em1(IMPC)Rbrc}	heterozygote	Late adult	N/A ^*
abnormal liver morphology	2 supporting datasets	Etv6^{em1(IMPC)Rbrc}	heterozygote	Late adult	N/A ^*
abnormal heart morphology	2 supporting datasets	Etv6^{em1(IMPC)Rbrc}	heterozygote	Late adult	N/A ^*
abnormal heart morphology	2 supporting datasets	Etv6^{em1(IMPC)Rbrc}	heterozygote	Early adult	N/A ^*
small liver	2 supporting datasets	Etv6^{em1(IMPC)Rbrc}	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Etv6.

Associated images

Loading...

Histopathology

There is no histopathology data found for Etv6.

IMPC related publications

Loading...

External links

No external links available for Etv6.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Etv6^{em1(IMPC)Rbrc}*	Indel	‌	mouse
*Etv6^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

My Genes