Ddit3 | DNA-damage inducible transcript 3

GeneMGI:109247Synonyms: CHOP10, CHOP-10, +3 more

Physiological systems

21 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Homeostasis/metabolism

20 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:1Significant phenotypes

1Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes



increased circulating aspartate transaminase level	1 supporting dataset		Ddit3^{tm1.1(KOMP)Vlcg}	homozygote	Early adult		6.1x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ddit3.

Associated images

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Histopathology

There is no histopathology data found for Ddit3.

IMPC related publications

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External links

No external links available for Ddit3.

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*Ddit3^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Ddit3^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Ddit3^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Ddit3^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Ddit3^{tm214450(L1L2_Bact_P)}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector

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