Npas2 | neuronal PAS domain protein 2
Physiological systems
20 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Immune system Integument Growth/size/body region Vision/eye Hematopoietic system Mortality/aging Renal/urinary system
13 No significant impact
4 Not tested
Data collections
Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal lymph node morphology | 1 supporting dataset | Npas2em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal skin morphology | 2 supporting datasets | Npas2em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| enlarged lymph nodes | 1 supporting dataset | Npas2em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Npas2em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| decreased lymphocyte cell number | 1 supporting dataset | Npas2em1(IMPC)Mbp | homozygote | Early adult | 4.35x10-5 | ||
| increased neutrophil cell number | 2 supporting datasets | Npas2em1(IMPC)Mbp | homozygote | Early adult | 6.36x10-7 | ||
| abnormal kidney morphology | 1 supporting dataset | Npas2em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| microphthalmia | 1 supporting dataset | Npas2em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| enlarged kidney | 1 supporting dataset | Npas2em1(IMPC)Mbp | homozygote | Early adult | N/A * |
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External links
No external links available for Npas2.
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| Npas2em1(IMPC)Mbp | Exon Deletion | | mouse |
| Npas2tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Npas2tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |