Cpt2 | carnitine palmitoyltransferase 2

GeneMGI:109176Synonyms: CPT II, CPTII

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Skeleton Mortality/aging

15 No significant impact

6 Not tested

Gene metrics:3Significant phenotypes
8Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

increased circulating phosphate level1 supporting datasetCpt2tm1b(KOMP)WtsiheterozygoteEarly adult9.55x10-7 
abnormal vertebrae morphology1 supporting datasetCpt2tm1b(KOMP)WtsiheterozygoteEarly adult3.88x10-6 
preweaning lethality, incomplete penetrance1 supporting datasetCpt2tm1b(KOMP)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cpt2tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Cpt2tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Cpt2tm1e(KOMP)WtsiTargeted, non-conditional allelees cell
Cpt2tm356689(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Cpt2tm36516(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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