Cpt2 | carnitine palmitoyltransferase 2

GeneMGI:109176Synonyms: CPT II, CPTII

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Skeleton Mortality/aging

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

8Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased circulating phosphate level	1 supporting dataset	Cpt2^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	9.55x10^-7
abnormal vertebrae morphology	1 supporting dataset	Cpt2^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	3.88x10^-6
preweaning lethality, incomplete penetrance	1 supporting dataset	Cpt2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cpt2.

Associated images

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Histopathology

There is no histopathology data found for Cpt2.

IMPC related publications

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External links

No external links available for Cpt2.

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*Cpt2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Cpt2^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Cpt2^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Cpt2^{tm356689(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Cpt2^{tm36516(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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