Dspp | dentin sialophosphoprotein

GeneMGI:109172Synonyms: Dmp3, Dpp, +1 more

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Mortality/aging Renal/urinary system

17 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

8Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



preweaning lethality, incomplete penetrance	1 supporting dataset	Dspp^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
abnormal kidney morphology	1 supporting dataset	Dspp^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
polycystic kidney	1 supporting dataset	Dspp^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
improved glucose tolerance	1 supporting dataset	Dspp^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	4.57x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dspp.

Associated images

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Histopathology

There is no histopathology data found for Dspp.

IMPC related publications

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External links

No external links available for Dspp.

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*Dspp^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Dspp^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse

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